期刊
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
卷 76, 期 2, 页码 129-132出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2013.02.012
关键词
Diagnosis; Paediatrics; Pneumococcal conjugate vaccine; Pneumonia; Serotype; Streptococcus pneumoniae; Urinary pneumococcal antigen
资金
- Pfizer Vaccines UK [0887X1-4479]
- Pfizer
The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced routinely in the UK from September 2006 and replaced by PCV13 in 2010. In a prospective study from 2009 to 2011 of 160 children aged <= 16 years with radiologically confirmed pneumonia, likely pneumococcal infections were identified in 26%. Detection of pneumococci was improved with polymerase chain reaction compared to culture (21.6% versus 6% of children tested, P = 0.0004). Where serotyping was possible, all (n = 23) were non-PCV7 but PCV13 serotypes; 1 (43.5%), 3 (21.7%), 7A/F, and 19A (17.4% each). (C) 2013 Elsevier Inc. All rights reserved.
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