Tn2008 is a major vehicle carrying blaOXA-23 in Acinetobacter baumannii from China

bla(OXA-23) and bla(OXA-66) were detected in 49 Acinetobacter baumannii isolates. These isolates were assigned to 7 subtypes by enterobacterial repetitive intergenic consensus polymerase chain reaction and 7 representative isolates were of ST92 or ST75. In most cases, the ISAbaI-bla(OXA-23)-ATPase Delta structure was identical to Tn2008. The 16-bp sequence at the left end of Tn2008 resembled the inverted repeat of ISAbaI, suggesting that ISAbaI might have utilized an alternative boundary to mobilize bla(OXA-23). (C) 2011 Elsevier Inc. All rights reserved.