期刊
DIAGNOSTIC CYTOPATHOLOGY
卷 42, 期 3, 页码 253-258出版社
WILEY-BLACKWELL
DOI: 10.1002/dc.22915
关键词
effusion; immunostaining; cytology; reactive mesothelial cells; adenocarcinoma cells
资金
- Intramural Research Program of the NIH (in part), National Cancer Institute
Distinguishing metastatic carcinoma cells from reactive mesothelial cells in effusion samples is often challenging based on morphology alone. Metastatic carcinoma cells in fluid samples may mimic reactive mesothelial cells due to overlapping cytological features. We report a case of a pleural effusion in a 51-year-old female patient with a medical history significant for bilateral ovarian tumors and peritoneal implants diagnosed as serous tumor of borderline malignant potential. The effusion was composed almost entirely of adenocarcinoma cells that morphologically mimicked reactive mesothelial cells. The diagnosis of metastatic adenocarcinoma was made after a wide immunostaining panel of antibodies. Recognizing metastatic adenocarcinoma cells in effusion samples can be challenging and an accurate diagnosis may have significant impact on clinical management as demonstrated by this case. Diagn. Cytopathol. 2012;42:253-258. (c) 2012 Wiley Periodicals, Inc.
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