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Jason Flannick et al.
NATURE GENETICS (2014)
When less is more: the forbidden fruits of gene repression in the adult β-cell
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DIABETES OBESITY & METABOLISM (2013)
The taste of heavy metals: Gene regulation by MTF-1
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Regulation and functional effects of ZNT8 in human pancreatic islets
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JOURNAL OF ENDOCRINOLOGY (2012)
Glucose-Induced O2 Consumption Activates Hypoxia Inducible Factors 1 and 2 in Rat Insulin-Secreting Pancreatic Beta-Cells
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PLOS ONE (2012)
The Physiological Effects of Deleting the Mouse Slc30a8 Gene Encoding Zinc Transporter-8 Are Influenced by Gender and Genetic Background
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PLOS ONE (2012)
Zinc Transporter 8 (ZnT8) Expression Is Reduced by Ischemic Insults: A Potential Therapeutic Target to Prevent Ischemic Retinopathy (Publication with Expression of Concern. See vol. 14, 2019)
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PLOS ONE (2012)
The pancreatic islet beta-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer
Lynley D. Pound et al.
BIOCHEMICAL JOURNAL (2011)
A Low-Oxygenated Subpopulation of Pancreatic Islets Constitutes a Functional Reserve of Endocrine Cells
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DIABETES (2011)
Increased Numbers of Low-Oxygenated Pancreatic Islets After Intraportal Islet Transplantation
Richard Olsson et al.
DIABETES (2011)
Nucleo-cytosolic Shuttling of FoxO1 Directly Regulates Mouse Ins2 but Not Ins1 Gene Expression in Pancreatic Beta Cells (MIN6)
Gargi Meur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Glucose Regulates Free Cytosolic Zn2+ Concentration, Slc39 (ZiP), and Metallothionein Gene Expression in Primary Pancreatic Islet β-Cells
Elisa A. Bellomo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretion in Vitro
Yoshifumi Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Connexins protect mouse pancreatic β cells against apoptosis
Philippe Klee et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR)
Daliang Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Unique Arrangement of α- and β-Cells in Human Islets of Langerhans
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DIABETES (2010)
Rat islet cell aggregates are superior to islets for transplantation in microcapsules
E. S. O'Sullivan et al.
DIABETOLOGIA (2010)
Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion
N. Wijesekara et al.
DIABETOLOGIA (2010)
Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic β-cell function
Malek El Muayed et al.
JOURNAL OF ENDOCRINOLOGY (2010)
Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes
Lorella Marselli et al.
PLOS ONE (2010)
Zinc Downregulates HIF-1α and Inhibits Its Activity in Tumor Cells In Vitro and In Vivo
Lavinia Nardinocchi et al.
PLOS ONE (2010)
Think zinc New roles for zinc in the control of insulin secretion
Guy A. Rutter
ISLETS (2010)
Oxygenation of islets and its role in transplantation
Joey Lau et al.
CURRENT OPINION IN ORGAN TRANSPLANTATION (2009)
Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants
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DIABETES (2009)
TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet beta-Cells
Gabriela da Silva Xavier et al.
DIABETES (2009)
Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis
Jan L. Vinkenborg et al.
NATURE METHODS (2009)
SLC30A3 Responds to Glucose- and Zinc Variations in β-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During β-Cell Stress
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PLOS ONE (2009)
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice
K. Lemaire et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?
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BMC ENDOCRINE DISORDERS (2009)
Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion
K. Kirchhoff et al.
DIABETOLOGIA (2008)
The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients -: the EUGENE2 study
T. W. Boesgaard et al.
DIABETOLOGIA (2008)
Collagenase Penetrates Human Pancreatic Islets Following Standard Intraductal Administration
Sarah E. Cross et al.
TRANSPLANTATION (2008)
ZnT5 variant B is a bidirectional zinc transporter and mediates zinc uptake in human intestinal Caco-2 cells
Ruth A. Valentine et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek et al.
NATURE (2007)
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function
O Cabrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
ZnT-8, a pancreatic beta-cell-specific zinc transporter
F Chimienti et al.
BIOMETALS (2005)
Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic α-cells
MA Ravier et al.
DIABETES (2005)
Rethinking the excitotoxic ionic milieu:: The emerging role of Zn2+ in ischemic neuronal injury
SL Sensi et al.
CURRENT MOLECULAR MEDICINE (2004)
Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species
XY Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mammalian zinc transporters
JP Liuzzi et al.
ANNUAL REVIEW OF NUTRITION (2004)
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes
I Chang et al.
DIABETOLOGIA (2003)
Regulation of insulin gene transcription
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DIABETOLOGIA (2002)
Zinc as a paracrine effector in pancreatic islet cell death
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DIABETES (2000)