相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Stimulation of Lipogenesis as Well as Fatty Acid Oxidation Protects against Palmitate-Induced INS-1 β-Cell Death
Sung-E. Choi et al.
ENDOCRINOLOGY (2011)
Both liver-X receptor (LXR) isoforms control energy expenditure by regulating Brown Adipose Tissue activity
Marion Korach-Andre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Molecular biology and functional genomics of liver X receptors (LXR) in relationship to metabolic diseases
Malin Hedengran Faulds et al.
CURRENT OPINION IN PHARMACOLOGY (2010)
Liver X Receptor Agonists Augment Human Islet Function through Activation of Anaplerotic Pathways and Glycerolipid/Free Fatty Acid Cycling
Takeshi Ogihara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest
Z. X. Meng et al.
DIABETOLOGIA (2009)
Elevated Insulin Secretion from Liver X Receptor-Activated Pancreatic β-Cells Involves Increased de Novo Lipid Synthesis and Triacylglyceride Turnover
Christopher D. Green et al.
ENDOCRINOLOGY (2009)
Susceptibility of Pancreatic Beta Cells to Fatty Acids Is Regulated by LXR/PPARα-Dependent Stearoyl-Coenzyme A Desaturase
Karine H. Hellemans et al.
PLOS ONE (2009)
Glucolipotoxicity:: Fuel excess and β-cell dysfunction
Vincent Poitout et al.
ENDOCRINE REVIEWS (2008)
Cholesterol in islet dysfunction and type 2 diabetes
Liam R. Brunham et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Sterol regulatory element-binding protein-1c and pancreatic β-cell dysfunction
H. Shimano et al.
DIABETES OBESITY & METABOLISM (2007)
The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population
T. K. Felder et al.
INTERNATIONAL JOURNAL OF OBESITY (2007)
Chronic activation of liver X receptor induces β-cell apoptosis through hyperactivation of lipogenesis -: Liver X receptor-mediated lipotoxicity in pancreatic β-cells
Sung Sik Choe et al.
DIABETES (2007)
Cell death and impairment of glucose-stimulated insulin secretion induced by 2,3,7,8-tetrachlorodibenzo-β-dioxin (TCDD) in the β-cell line INS-1E
Simona Piaggi et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells
Wolf Wente et al.
ENDOCRINOLOGY (2007)
The nuclear receptor LXR is a glucose sensor
Nico Mitro et al.
NATURE (2007)
Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus
S. Ferderbar et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2007)
Prostaglandin E2 regulates Foxo activity via the Akt pathway:: implications for pancreatic islet beta cell dysfunction
Z. X. Meng et al.
DIABETOLOGIA (2006)
The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317
Saswata Talukdar et al.
JOURNAL OF LIPID RESEARCH (2006)
Insulin induction of glucokinase and fatty acid synthase in hepatocytes: analysis of the roles of sterol-regulatory-element-binding protein-1c and liver X receptor
Franck Hansmannel et al.
BIOCHEMICAL JOURNAL (2006)
Sterol regulatory element-binding protein 1 mediates liver X receptor-β-induced increases in insulin secretion and insulin messenger ribonucleic acid levels
Heike Zitzer et al.
ENDOCRINOLOGY (2006)
Islet β cell failure in type 2 diabetes
Marc Prentki et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
LXRβ is required for adipocyte growth, glucose homeostasis, and β cell function
I Gerin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Pathogenesis of type 2 diabetes mellitus
JL Leahy
ARCHIVES OF MEDICAL RESEARCH (2005)
Functional and molecular defects of pancreatic islets in human type 2 diabetes
S Del Guerra et al.
DIABETES (2005)
Adipocytic differentiation and liver X receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells
JD Davies et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Transgenic mice overexpressing nuclear SREBP-1c in pancreatic β-cells
A Takahashi et al.
DIABETES (2005)
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor γ expression
JB Seo et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release:: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)
F Diraison et al.
BIOCHEMICAL JOURNAL (2004)
Putative metabolic effects of the liver x receptor (LXR)
KR Steffensen et al.
DIABETES (2004)
Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic β-cells
M Nenquin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic β-cells
AM Efanov et al.
DIABETES (2004)
Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet β cells
E Bernal-Mizrachi et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Liver X receptors as potential therapeutic targets for multiple diseases
GQ Cao et al.
DRUG NEWS & PERSPECTIVES (2004)
The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse
JW Chisholm et al.
JOURNAL OF LIPID RESEARCH (2003)
Gliclazide produces high-affinity block of KATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells
CL Lawrence et al.
DIABETOLOGIA (2001)
New perspectives into the molecular pathogenesis and treatment of Type 2 diabetes
AR Saltiel
CELL (2001)
Triggering and amplifying pathways of regulation of insulin secretion by glucose
JC Henquin
DIABETES (2000)
Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets
T Kakuma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Plasma oxysterols and tocopherol in patients with diabetes mellitus and hyperlipidemia
H Murakami et al.
LIPIDS (2000)