相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Intramuscular triacylglycerol and insulin resistance: Guilty as charged or wrongly accused?
Deborah M. Muoio
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Mice Lacking Hepatic Lipase Are Lean and Protected against Diet-Induced Obesity and Hepatic Steatosis
Harvey K. Chiu et al.
ENDOCRINOLOGY (2010)
How mitochondria produce reactive oxygen species
Michael P. Murphy
BIOCHEMICAL JOURNAL (2009)
Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet-Induced Insulin Resistance
Clinton R. Bruce et al.
DIABETES (2009)
Deletion of PKCε Selectively Enhances the Amplifying Pathways of Glucose-Stimulated Insulin Secretion via Increased Lipolysis in Mouse β-Cells
James Cantley et al.
DIABETES (2009)
Diverse roles for protein kinase C δ and protein kinase C ε in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C δ
G. Frangioudakis et al.
DIABETOLOGIA (2009)
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
Timothy R. Koves et al.
CELL METABOLISM (2008)
IRS1-independent defects define major nodes of insulin resistance
Kyle L. Hoehn et al.
CELL METABOLISM (2008)
Protein kinase C function in muscle, liver, and β-cells and its therapeutic implications for type 2 diabetes
Carsten Schmitz-Peiffer et al.
DIABETES (2008)
Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice
Kaori Minehira et al.
JOURNAL OF LIPID RESEARCH (2008)
Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity
Cheol Soo Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Inhibition of PKCε improves glucose-stimulated insulin secretion and reduces insulin clearance
Carsten Schmitz-Peiffer et al.
CELL METABOLISM (2007)
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
Takashi Matsuzaka et al.
NATURE MEDICINE (2007)
The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle
Asha Seth et al.
CELL METABOLISM (2007)
Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity
P. Newsholme et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle - Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
Nigel Turner et al.
DIABETES (2007)
Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle
R. Cazzolli et al.
DIABETOLOGIA (2007)
Metabolic stress in insulin's target cells leads to ROS accumulation - A hypothetical common pathway causing insulin resistance
Jan W. Eriksson
FEBS LETTERS (2007)
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
Mara Monetti et al.
CELL METABOLISM (2007)
Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice
J. Cantley et al.
DIABETOLOGIA (2007)
Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease
Varman T. Samuel et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
Katsutaro Morino et al.
DIABETES (2006)
Protein kinase Cζ and glucose uptake
Li-Zhong Liu et al.
BIOCHEMISTRY-MOSCOW (2006)
Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose:: Involvement of sterol regulatory element-binding protein-1c
Y Achouri et al.
BIOCHIMIE (2005)
Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic β-cells from lipoapoptosis
AK Busch et al.
DIABETES (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
A potential link between muscle peroxisome proliferator-activated receptor-α signaling and obesity-related diabetes
BN Finck et al.
CELL METABOLISM (2005)
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
VT Samuel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Increased β-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
G Perdomo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
M Matsumoto et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
DG Hardie et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
PPAR-α-null mice are protected from high-fat diet-induced insulin resistance
M Guerre-Millo et al.
DIABETES (2001)
PPARα deficiency reduces insulin resistance and atherosclerosis in apoE-null mice
K Tordjman et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus -: Overexpression of protein kinase Cε in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia
Y Ikeda et al.
DIABETES (2001)