相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Potential Role for Dendritic Cell/Macrophage-Expressing DPP4 in Obesity-Induced Visceral Inflammation
Jixin Zhong et al.
DIABETES (2013)
EFFECT OF SITAGLIPTIN ON POSTPRANDIAL GLUCAGON AND GLP-1 LEVELS IN PATIENTS WITH TYPE 1 DIABETES: INVESTIGATOR-INITIATED, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL
Satish K. Garg et al.
ENDOCRINE PRACTICE (2013)
CD26-mediated co-stimulation in human CD8+T cells provokes effector function via pro-inflammatory cytokine production
Ryo Hatano et al.
IMMUNOLOGY (2013)
Helper T cell diversity and plasticity
Shingo Nakayamada et al.
CURRENT OPINION IN IMMUNOLOGY (2012)
Long-Term Remission of Diabetes in NOD Mice Is Induced by Nondepleting Anti-CD4 and Anti-CD8 Antibodies
Zuoan Yi et al.
DIABETES (2012)
Administration of CD4+CD25highCD127- Regulatory T Cells Preserves β-Cell Function in Type 1 Diabetes in Children
Natalia Marek-Trzonkowska et al.
DIABETES CARE (2012)
Combined treatment with a dipeptidyl peptidase-IV inhibitor (sitagliptin) and an angiotensin II type 1 receptor blocker (losartan) promotes islet regeneration via enhanced differentiation of pancreatic progenitor cells
J. Liang et al.
DIABETES OBESITY & METABOLISM (2012)
Treatment of autoimmune diabetes in NOD mice by Toll-like receptor 2 tolerance in conjunction with dipeptidyl peptidase 4 inhibition
D. -H. Kim et al.
DIABETOLOGIA (2012)
Enhanced ovalbumin-induced airway inflammation in CD26-/- mice
Shuling Yan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
The DPP4 inhibitor linagliptin delays the onset of diabetes and preserves β-cell mass in non-obese diabetic mice
Jacob Jelsing et al.
JOURNAL OF ENDOCRINOLOGY (2012)
Human Th17 Cells Express High Levels of Enzymatically Active Dipeptidylpeptidase IV (CD26)
Bertram Bengsch et al.
JOURNAL OF IMMUNOLOGY (2012)
Combination Therapy With a Dipeptidyl Peptidase-4 Inhibitor and a Proton Pump Inhibitor Induces beta-Cell Neogenesis From Adult Human Pancreatic Duct Cells Implanted in Immunodeficient Mice
Wilma L. Suarez-Pinzon et al.
CELL TRANSPLANTATION (2011)
Long-Term Dipeptidyl-Peptidase 4 Inhibition Reduces Atherosclerosis and Inflammation via Effects on Monocyte Recruitment and Chemotaxis
Zubair Shah et al.
CIRCULATION (2011)
Effect of sitagliptin on glucose control in adult patients with Type 1 diabetes: a pilot, double-blind, randomized, crossover trial
S. L. Ellis et al.
DIABETIC MEDICINE (2011)
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions
Aliza Biton et al.
IMMUNOBIOLOGY (2011)
Altered Proportions of Na⟨ve, Central Memory and Terminally Differentiated Central Memory Subsets among CD4+ and CD8+ T Cells Expressing CD26 in Patients with Type 1 Diabetes
Elena Matteucci et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2011)
Reduced airway inflammation in CD26/DPP4-deficient F344 rats is associated with altered recruitment patterns of regulatory T cells and expression of pulmonary surfactant proteins
A. Schmiedl et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2010)
Sitagliptin (MK0431) Inhibition of Dipeptidyl Peptidase IV Decreases Nonobese Diabetic Mouse CD4+ T-Cell Migration Through Incretin-Dependent and -Independent Pathways
Su-Jin Kim et al.
DIABETES (2010)
Reversal of New-Onset Diabetes through Modulating Inflammation and Stimulating β-Cell Replication in Nonobese Diabetic Mice by a Dipeptidyl Peptidase IV Inhibitor
Lei Tian et al.
ENDOCRINOLOGY (2010)
Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25highFOXP3+ Regulatory T Cells
Magis Mandapathil et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
IL-17 Immunity in Human Type 1 Diabetes
Jarno Honkanen et al.
JOURNAL OF IMMUNOLOGY (2010)
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
Kajsa Wing et al.
NATURE IMMUNOLOGY (2010)
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses
Kalpit A. Vora et al.
BMC IMMUNOLOGY (2009)
Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice
Dirk Reinhold et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2009)
Dipeptidyl Peptidase IV Inhibition With MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-Cell Modulation
Su-Jin Kim et al.
DIABETES (2009)
Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice
Juliet A. Emamaullee et al.
DIABETES (2009)
Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor restores normoglycaemia in non-obese diabetic mice
W. L. Suarez-Pinzon et al.
DIABETOLOGIA (2009)
Treatment with the Dipeptidyl Peptidase-4 Inhibitor Vildagliptin Improves Fasting Islet-Cell Function in Subjects with Type 2 Diabetes
David A. D'Alessio et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function
Mark D. Pescovitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis
Dirk Reinhold et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes
J. E. Foley et al.
HORMONE AND METABOLIC RESEARCH (2008)
Immunology - T cells hang in the balance
Emily A. Stevens et al.
NATURE (2008)
Revisiting an old acquaintance: CD26 and its molecular mechanisms in T cell function
Kei Ohnuma et al.
TRENDS IN IMMUNOLOGY (2008)
Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance
Julio Rosenstock et al.
DIABETES CARE (2008)
Biology of incretins: GLP-1 and GIP
Laurie L. Baggio et al.
GASTROENTEROLOGY (2007)
TGF-β1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26
Vera Preller et al.
JOURNAL OF IMMUNOLOGY (2007)
TH-17 cells in the circle of immunity and autoimmunity
Estelle Bettelli et al.
NATURE IMMUNOLOGY (2007)
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/CD13) -: A novel approach for the treatment of inflammatory bowel disease
Ute Bank et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2006)
Effects of autoimmunity and immune therapy on β-cell turnover in type 1 diabetes
Nicole A. Sherry et al.
DIABETES (2006)
CD4+memory T cells with high CD26 surface expression are enriched for Th1 markers and correlate with clinical severity of multiple sclerosis
M. Krakauer et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes
Gary A. Herman et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic β-cell mass and function in a rodent model of type 2 diabetes
James Mu et al.
DIABETES (2006)
TGF-β signaling is required for the function of insulin-reactive T regulatory cells
W Du et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Th17: An effector CD4 T cell lineage with regulatory T cell ties
Casey T. Weaver et al.
IMMUNITY (2006)
Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses
GA Herman et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed β-cell function in patients with type 2 diabetes
A Mari et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
S Lindley et al.
DIABETES (2005)
TGF-β regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
YF Peng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Localization, transmission, spontaneous mutations, and variation of function of the Dpp4 (Dipeptidyl-peptidase IV; CD26) gene in rats
T Karl et al.
REGULATORY PEPTIDES (2003)
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
M Belghith et al.
NATURE MEDICINE (2003)
Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen
SL Yan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance
SL Conarello et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Dipeptidyl peptidase IV inhibitor treatment stimulates β-cell survival and islet neogenesis in streptozotocin-induced diabetic rats
JA Pospisilik et al.
DIABETES (2003)
CD26/DPPIV signal transduction function, but not proteolytic activity, is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry
EP Boonacker et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2002)
T-cell immune parameters and depression in patients with Crohn's disease
M Rose et al.
JOURNAL OF CLINICAL GASTROENTEROLOGY (2002)
Targeting dipeptidyl peptidase IV (CD26) suppresses autoimmune encephalomyelitis and up-regulates TGF-β1 secretion in vivo
A Steinbrecher et al.
JOURNAL OF IMMUNOLOGY (2001)
Mechanisms of CD26/dipeptidyl peptidase IV cytokine-dependent regulation on human activated lymphocytes
FJ Salgado et al.
CYTOKINE (2000)
Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
L Gorelik et al.
IMMUNITY (2000)