期刊
DIABETES-METABOLISM RESEARCH AND REVIEWS
卷 28, 期 -, 页码 27-29出版社
WILEY
DOI: 10.1002/dmrr.2232
关键词
arterial occlusion; arteriogenesis; fluid shear stress; nitric oxide; angiogenesis
Different forms of vessel growth in the adult organism contribute to the compensation for an occluded artery. We here summarize the major differences between arteriogenesis and angiogenesis and provide evidence in favour of a therapeutic stimulation of collateral growth. In addition, we outline current knowledge about regulatory mechanisms transducing the initial physical stimulus into a cellular response. As an example, the role of nitric oxide during arteriogenesis is discussed, and finally, we propose a mechanism of how an efficient decision is made that makes the larger collaterals larger and the smaller ones smaller. Copyright (C) 2012 John Wiley & Sons, Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据