期刊
DIABETES RESEARCH AND CLINICAL PRACTICE
卷 97, 期 1, 页码 132-138出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2012.04.022
关键词
The triglyceride to high-density lipoprotein cholesterol ratio; Insulin resistance; HOMA-IR
Aims: This study explores the association between the ratio of triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) and insulin resistance according to waist circumference in the general Korean population. Methods: 7623 participants were selected from the Korean National Health and Nutrition Examination Survey (KNHANES) conducted during 2007-2009 and included in this cross-sectional study. Insulin resistance was defined as the values equal to or greater than the 75th percentile of the homeostasis model assessment of insulin resistance (HOMA-IR). Results: Positive correlation was found between the ratio of TG and HDL-C and other variables such as waist circumference, total cholesterol, and HOMA-IR for both men and women. The odds ratios (ORs) (95% confidence interval) for insulin resistance for the highest quartile of TG/HDL-C were 2.48 in men and 3.05 in women. The significant relationship between the TG/HDL-C ratio and insulin resistance was not only maintained across all quartiles of waist circumference but also seemed to be enhanced in the higher quartiles of waist circumference. Conclusion: In the general Korean population, there seems to be a linear association between TG/HDL-C ratio and insulin resistance, regardless of degrees of waist circumference. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
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