期刊
DIABETES RESEARCH AND CLINICAL PRACTICE
卷 98, 期 3, 页码 E23-E27出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2012.09.044
关键词
Diabetes; Genome wide association; Replication; TCF7L2
资金
- AGU REC
We tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695-rs4506565-rs7903146-rs12243326-rs7895340-rs11196205-rs12255372) identified positively- (2122112, 2222222) and negatively- (1111111) T2DM-associated haplotypes. TCF7L2 is a common T2DM candidate gene in Lebanese people. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
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