期刊
DIABETES CARE
卷 34, 期 4, 页码 813-817出版社
AMER DIABETES ASSOC
DOI: 10.2337/dc10-1772
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资金
- Centre de Recherche et d'Information Nutritionnelles (CERIN)-Centre National Interprofessionnel de l'Economie Laitiere (CNIEL)
- INSERM
- Caisse Nationale d'Assurance Maladie des Travailleurs Salar
- INSERM (Reseaux en Sante Publique, Interactions entre les determinants de la sante)
- Cohortes Sante TGIR
- Association Diabete Risque Vasculaire
- La Fondation de France
- l'Association de Langue Francaise pour l'Etude du Diabete et des Maladies Metaboliques
- Office National Interprofessionnel des Vins
- Eli Lilly and Co.
- Novartis Pharmaceuticals
- sanofi-aventis
- Ardix Medical
- Bayer Diagnostics
- Becton, Dickinson and Company
- Cardionics
- Merck Sante
- Novo Nordisk
- Pierre Fabre
- Roche
- Topcon Medical Systems
OBJECTIVE-In the French Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort, cross-sectional analyses have shown that a higher consumption of dairy products and calcium are associated with a lower prevalence of the metabolic syndrome (MetS). We assess the influence of dairy products on 9-year incident MetS and on impaired fasting glycemia and/or type 2 diabetes (IFG/T2D). RESEARCH DESIGN AND METHODS-Men and women who completed a food frequency questionnaire at baseline and after 3 years were studied (n = 3,435). Logistic regression models were used to study associations between the average year 0 and year 3 consumption of milk and dairy products, cheese, dietary calcium density, and incident MetS and IFG/T2D after adjusting for 1) sex, age, alcohol, smoking, physical activity, fat intake and 2) additionally for BMI. Associations between dairy products and continuous variables were studied by repeated-measures ANCOVA, using the same covariates. RESULTS-Dairy products other than cheese, and dietary calcium density, were inversely associated with incident MetS and IFG/T2D, cheese was negatively associated with incident MetS. All three parameters were associated with lower diastolic blood pressure, and with a lower EM! gain. Higher cheese intake and calcium density were associated with a lower increase in waist circumference and lower triglyceride levels. Calcium density was also associated with a lower systolic blood pressure and a lower 9-year increase in plasma triglyceride levels. CONCLUSIONS-A higher consumption of dairy products and calcium was associated with a lower 9-year incidence of MetS and IFG/T2D in a large cohort drawn from the general population. Diabetes Care 34:813-817, 2011
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