4.7 Article

Effect of Socioeconomic Status on Mortality Among People With Type 2 Diabetes A study from the Scottish Diabetes Research Network Epidemiology Group

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DIABETES CARE
卷 34, 期 5, 页码 1127-1132

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AMER DIABETES ASSOC
DOI: 10.2337/dc10-1862

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  1. Wellcome Trust [WT086113]
  2. Scottish Government
  3. NHS Research Scotland (NRS), through the Scottish Diabetes Research Network

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OBJECTIVE-The study objective was to describe the effect of socioeconomic status (SES) on mortality among people with type 2 diabetes. RESEARCH DESIGN AND METHODS-We used a population-based national electronic diabetes database for 35- to 84-year-olds in Scotland for 2001-2007 linked to mortality records. SES was derived from an area-based measure with Q5 and Q1 representing the most deprived and affluent quintiles, respectively. Poisson regression was used to estimate relative risks (RRs) for mortality among people with type 2 diabetes compared with the population without diabetes stratified by age (35-64 and 65-84 years), sex, duration of diabetes (< 2 and >= 2 years), and SES. RESULTS-Complete data were available for 210,994 eligible individuals (99.4%), and there were 33,842 deaths. Absolute mortality from all causes among people with type 2 diabetes increased with increasing age and socioeconomic deprivation and was higher for men than women. RR for mortality associated with type 2 diabetes was highest for women aged 35-64 years in Q1 with diabetes duration < 2 years at 4.83(95% CI 3.15-7.40) and lowest for men aged 65-84 years in Q5 with diabetes duration >= 2 years at 1.13 (1.03-1.24). CONCLUSIONS-SES modifies the association between type 2 diabetes and mortality so that RR for mortality is lower among more deprived populations. Age, sex, and duration of diabetes also interact with type 2 diabetes to influence RR of mortality. Differences in prevalence of comorbidities may explain these findings.

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