4.7 Article

Rising Rates of All Types of Diabetes in South Asian and Non-South Asian Children and Young People Aged 0-29 Years in West Yorkshire, U.K., 1991-2006

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DIABETES CARE
卷 34, 期 3, 页码 652-654

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AMER DIABETES ASSOC
DOI: 10.2337/dc10-1512

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  1. NHS Diabetes

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OBJECTIVE-To investigate incidence trends of all diabetes types in all children and young people and in the south Asian subpopulation. RESEARCH DESIGN AND METHODS-Annual incidence per 100,000 and time trends (1991-2006) were analyzed for 2,889 individuals aged 0-29 years diagnosed with diabetes while resident in West Yorkshire, U.K. RESULTS-Diagnoses comprised type 1(83%), type 2 (12%), maturity-onset diabetes of the young (0.7%), J-type/other (0.1%), and uncertain/unclassified (4%). There was a lower incidence of type 1 and a threefold excess of type 2 in south Asians compared with non-south Asians. Type 1 incidence leveled out and type 2 increased after the first south Asian case of type 2 was diagnosed in 1999. Type 2 and unclassified diabetes incidence rose in all population subgroups. CONCLUSIONS-The burden of diabetes increased over time for both ethnic groups, with a significant excess of type 2 diabetes in south Asians. The rising incidence of type 1 diabetes in south Asians attenuated as type 2 diabetes increased after 1999.

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