期刊
DIABETES CARE
卷 33, 期 6, 页码 1239-1241出版社
AMER DIABETES ASSOC
DOI: 10.2337/dc10-0347
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-
资金
- National Health and Medical Research Council of Australia [573122, 471409]
OBJECTIVE - To examine the effect of childbearing and maternal breastfeeding on a woman's subsequent risk of developing type 2 diabetes. RESEARCH DESIGN AND METHODS - Using information on parity, breastfeeding, and diabetes collected from 52,731 women recruited into a cohort study, we estimated the risk of type 2 diabetes using multivariate logistic regression. RESULTS - A total of 3,160(6.0%) women were classified as having type 2 diabetes. Overall, nulliparous and parous women had a similar risk of diabetes. Among parous women, there was a 14% (95% CI 10-18%, P<0.001) reduced likelihood of diabetes per year of breastfeeding. Compared to nulliparous women, parous women who did not breastfeed had a greater risk of diabetes (odds ratio 1.48,95% CI 1.26-1.73, P<0.001), whereas for women breastfeeding, the risk was not significantly increased. CONCLUSIONS - Compared with nulliparous women, childbearing women who do not breastfeed have about a 50% increased risk of type 2 diabetes in later life. Breastfeeding substantially reduces this excess risk.
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