4.7 Article

Type 2 Diabetes Prevention in the Real World Three-year results of the GOAL Lifestyle Implementation Trial

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DIABETES CARE
卷 32, 期 8, 页码 1418-1420

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AMER DIABETES ASSOC
DOI: 10.2337/dc09-0039

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  1. Academy of Finland
  2. Social Insurance Agency
  3. Finnish Ministry of Social Affairs and Health

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OBJECTIVE - We study the effectiveness of the GOAL Lifestyle Implementation Trial at the 36-month follow-up. RESEARCH DESIGN AND METHODS - Participants (n = 352, type 2 diabetes risk score FINDRISC = 16.2 +/- 3.3, BMI 32.6 +/- 5.0 kg/m(2)) received six lifestyle counseling sessions over 8 months. Measurements were at baseline, 12 months (88.6%), and 36 months (77.0%). RESULTS - Statistically significant risk reduction at 12 months was maintained at 36 months in weight (-1.0 +/- 5.6 kg), BMI (-0.5 +/- 2.1 kg/m(2)), and serum total cholesterol (-0.4 +- 1.1 mmol/l). CONCLUSIONS - Maintenance of risk reduction in this real world trial proves the intervention's potential for significant public health impact.

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