4.7 Article Proceedings Paper

Obstructive Sleep Apnea Among Obese Patients With Type 2 Diabetes

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DIABETES CARE
卷 32, 期 6, 页码 1017-1022

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AMER DIABETES ASSOC
DOI: 10.2337/dc08-1776

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资金

  1. NHLBI NIH HHS [R01 HL070301, HL070301] Funding Source: Medline
  2. NIDDK NIH HHS [U01 DK056992, DK057135, DK56992, U01 DK057135, DK60426] Funding Source: Medline

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OBJECTIVE - To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - Unattended polysomnography was performed in 306 participants. RESULTS - Over 86% of participants had OSA with an apnea-hypopnea index (AHI) >= 5 events/h. The mean AHI was 20.5 +/- 16.8 events/h. A total of 30.5% of the participants had moderate OSA (1.5 <= AHI <30), and 22.6% had severe OSA (AHI >= 30). Waist circumference (odds ratio 1.1; 95% CL 1.0-1.1.; P = 0.03) was significantly related to the presence of OSA. Severe OSA was most likely in individuals with a higher BMI (odds ratio 1.1; 95% Cl 1..0-1.2; P = 0.03). CONCLUSIONS - Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among individuals with higher waist. circumference and BMI. Diabetes Care 32:1.0.1.7-1019, 2009

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