4.7 Article

Diabetes in African American Youth Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study

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DIABETES CARE
卷 32, 期 -, 页码 S112-S122

出版社

AMER DIABETES ASSOC
DOI: 10.2337/dc09-S203

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资金

  1. Centers for Disease Control and Prevention [00097, DP-05-069]
  2. National Institute of Diabetes and Digestive and Kidney Diseases
  3. Kaiser Permanente Southern California [U01 DP000246]
  4. University Of Colorado Health Sciences Center [U01 DP000247]
  5. Pacific Health Research Institute [1101 DP000245]
  6. Children's Hospital Medical Center (Cincinnati) [U01 DP000248]
  7. University of North Carolina [U01 DP000254]
  8. University of Washington School of Medicine [U01 DP000244, M01 RR00037, M01 RR001271]
  9. Wake Forest University School of Medicine [U01 DP000250]
  10. Medical University of South Carolina [M01 RR01070]
  11. Cincinnati Children's Hospital [M01 RRO8084]
  12. Children's Hospital and Regional Medical Center
  13. Colorado Pedi atric General Clinical Research Center [M01 RR00069]

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OBJECTIVE - To report the prevalence and incidence of type I and type 2 diabetes among African American youth and to describe demographic, clinical, and behavioral characteristics. RESEARCH DESIGN AND METHODS - Data from the SEARCH for Diabetes in Youth Study, a population-based, multicenter observational study of youth with clinically diagnosed diabetes aged 0-19 years, were used to estimate the prevalence for calendar year 2001 (692 cases) and incidence based on 748 African American case subjects diagnosed in 2002-2005. Characteristics of these youth were obtained during a research visit for 436 African American youth with type 1 diabetes and 212 African American youth with type 2 diabetes. RESULTS - Among African American youth aged 0-9 years, prevalence (per 1,000) of type I diabetes was 0.57 (95% CI 0.47-0.69) and for those aged 10-19 years 2.04 (1.85-2.26). Among African American youth aged 0-9 years, annual type I diabetes incidence (per 100,000) was 15.7 (13.7-17.9) and for those aged 10-19 years 15.7 (13.8-17.8). A1C was >= 9.5% among 50% of youth with type I diabetes aged >= 15 years. Across age-groups and sex, 44.7% of African American youth with type 1 diabetes were over-weight or obese. Among African American youth aged 10-19 years, prevalence (per 1,000) of type 2 diabetes was 1.06 (0.93-1.22) and annual incidence (per 100,000) was 19.0 (16.9-21.3). About 60% of African American youth with type 2 diabetes had an annual household income of <$25,000. Among those aged >= 15 years, 27.5% had an A1C >= 9.5%, 22.5% had high blood pressure, and, across subgroups of age and sex, >90% were overweight or obese. CONCLUSIONS - Type 1 diabetes presents a serious burden among African American youth aged < 10 years, and African American adolescents are impacted substantially by both type 1 and type 2 diabetes. Diabetes Care 32 (Suppl. 2):S112-S122, 2009

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