期刊
DIABETES CARE
卷 33, 期 1, 页码 101-103出版社
AMER DIABETES ASSOC
DOI: 10.2337/dc09-1366
关键词
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资金
- National Institutes of Health/National Institute on Aging [AG07181, AG028507]
- National Institute of Diabetes and Digestive and Kidney Diseases [DK31801]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) Brazil
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK031801] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [R37AG007181, R01AG028507, R01AG007181] Funding Source: NIH RePORTER
OBJECTIVE - To examine the sensitivity and specificity of A1C as a diagnostic Lest for type 2 diabetes in older adults. RESEARCH DESIGN AND METHODS - Cross-sectional study of community-dwelling adults without known diabetes who had an oral glucose tolerance test and A I C measured on the same day. RESULTS - Mean age of the 2,107 participants was 69.4 +/- 11.1 years; 43% were men. Based on the American Diabetes Association (ADA) criteria, 198 had previously undiagnosed type 2 diabetes. The sensitivity/specificity of A1C cut point of 6.5% was 44/79%. Results were similar in age- and sex-stratified analyses. Given the A1C cut point of 6.5%, 85% of participants were classified as nondiabetic by ADA criteria. CONCLUSIONS - The limited sensitivity of the A1C test may result in delayed diagnosis of type 2 diabetes, while the strict use of ADA criteria may fail to identify a high proportion of individuals with diabetes by A1C >= 6.5% or retinopathy.
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