相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction
Lea Rahtu-Korpela et al.
DIABETES (2014)
Adipose Vascular Endothelial Growth Factor Regulates Metabolic Homeostasis through Angiogenesis
Hoon-Ki Sung et al.
CELL METABOLISM (2013)
Prolyl Hydroxylase Domain Protein 2 Plays a Critical Role in Diet-Induced Obesity and Glucose Intolerance
Hirohide Matsuura et al.
CIRCULATION (2013)
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
Peter J. Ratcliffe
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
Tammie Bishop et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Selective Inhibition of Hypoxia-Inducible Factor 1α Ameliorates Adipose Tissue Dysfunction
Kai Sun et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection
Risto Kerkela et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Fat Depots, Free Fatty Acids, and Dyslipidemia
Jon O. Ebbert et al.
NUTRIENTS (2013)
Activation of Hypoxia-Inducible Factor-2 in Adipocytes Results in Pathological Cardiac Hypertrophy
Qun Lin et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance
Ivet Elias et al.
DIABETES (2012)
Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
Jaya Krishnan et al.
GENES & DEVELOPMENT (2012)
Adipocyte lipases and lipid droplet-associated proteins: insight from transgenic mouse models
A. Girousse et al.
INTERNATIONAL JOURNAL OF OBESITY (2012)
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
Zoi Michailidou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Dichotomous effects of VEGF-A on adipose tissue dysfunction
Kai Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
HIF1 alpha and HIF2 alpha: sibling rivalry in hypoxic tumour growth and progression
Brian Keith et al.
NATURE REVIEWS CANCER (2012)
Regulation of HIF-1α activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia
Qing He et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
Julie Adam et al.
CANCER CELL (2011)
The Differential Role of Hif1 β/Arnt and the Hypoxic Response in Adipose Function, Fibrosis, and Inflammation
Kevin Y. Lee et al.
CELL METABOLISM (2011)
Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity
Olga Gealekman et al.
CIRCULATION (2011)
Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet-Fed Mice
Changtao Jiang et al.
DIABETES (2011)
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
Ya-Min Tian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Adipose tissue remodeling and obesity
Kai Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome - An allostatic perspective
Sam Virtue et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice
Xinmei Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets
Kim Cheng et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Oxygen homeostasis
Gregg L. Semenza
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2010)
Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
Massimiliano Mazzone et al.
CELL (2009)
Hypoxia Decreases Insulin Signaling Pathways in Adipocytes
Claire Regazzetti et al.
DIABETES (2009)
Reduced Adipose Tissue Oxygenation in Human Obesity Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
Magdalena Pasarica et al.
DIABETES (2009)
Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue
Nils Halberg et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
Peter Fraisl et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration
M. E. Rausch et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions
Z. Elizabeth Floyd et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Acute postnatal ablation of Hif-2α results in anemia
Michaela Gruber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Angiogenesis modulates adipogenesis and obesity
Yihai Cao
JOURNAL OF CLINICAL INVESTIGATION (2007)
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
Naomi Hosogai et al.
DIABETES (2007)
EPAS1 promotes adipose differentiation in 3T3-L1 cells
S Shimba et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Adipokines: inflammation and the pleiotropic role of white adipose tissue
P Trayhurn et al.
BRITISH JOURNAL OF NUTRITION (2004)
Modulating the hypoxia-inducible factor signaling pathway: Applications from cardiovascular disease to cancer
KS Hewitson et al.
CURRENT PHARMACEUTICAL DESIGN (2004)
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
WM He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Sequence determinants in hypoxia-inducible factor-1α for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3
JH Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Adipose tissue mass can be regulated through the vasculature
MA Rupnick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: A mechanism for regulation of adipogenesis by hypoxia
Z Yun et al.
DEVELOPMENTAL CELL (2002)
A conserved family of prolyl-4-hydroxylases that modify HIF
RK Bruick et al.
SCIENCE (2001)
C-elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
ACR Epstein et al.
CELL (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
分享论文
