期刊
DEVELOPMENTAL NEUROSCIENCE
卷 31, 期 4, 页码 332-341出版社
KARGER
DOI: 10.1159/000216544
关键词
Oxytocin; Vasopressin; Pitocin; Sex differences; Early experience; Prairie voles
资金
- National Institutes of Health [HD38490, MH073022, HD08702, MH018882, MH072109]
- National Science Foundation [0437532]
- Institute for Research on Unlimited Love
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [P01HD038490, F32HD008702] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [T32MH018882, R01MH073022, F32MH072109] Funding Source: NIH RePORTER
In the socially monogamous prairie vole, we have observed that small changes in early handling, as well as early hormonal manipulations can have long-lasting and sexually dimorphic effects on behavior. These changes may be mediated in part by changes in parental interactions with their young, acting on systems that rely on oxytocin (OT) and arginine vasopressin (AVP). Knowledge of both endogenous and exogenous influences on systems that rely on OT and AVP may be helpful in understanding sexually dimorphic developmental disorders, such as autism, that are characterized by increased anxiety and deficits in social behavior. Copyright (C) 2009 S. Karger AG, Basel
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