期刊
DEVELOPMENTAL CELL
卷 22, 期 1, 页码 12-23出版社
CELL PRESS
DOI: 10.1016/j.devcel.2011.12.003
关键词
-
资金
- NIH
- Burroughs-Wellcome Trust
- American Heart Association
- Berkeley Graduate Fellowship
Tissue and organ architectures are incredibly diverse, yet our knowledge of the morphogenetic behaviors that generate them is relatively limited. Recent studies have revealed unexpected mechanisms that drive axis elongation in the Drosophila egg, including an unconventional planar polarity signaling pathway, a distinctive type of morphogenetic movement termed global tissue rotation, a molecular corset-like role of extracellular matrix, and oscillating basal cellular contractions. We review here what is known about Drosophila egg elongation, compare it to other instances of morphogenesis, and highlight several issues of general developmental relevance.
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