期刊
DEVELOPMENTAL CELL
卷 23, 期 5, 页码 919-921出版社
CELL PRESS
DOI: 10.1016/j.devcel.2012.10.024
关键词
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资金
- NIGMS NIH HHS [R01 GM080484] Funding Source: Medline
Upon binding to a promoter, RNA polymerase II can synthesize either a coding mRNA or a divergently transcribed noncoding RNA. In a recent issue of Science, Tan-Wong et al. (2012) find that intragenic looping increases the proper orientation of RNA polymerase II, reducing the production of divergent noncoding transcripts.
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