Subversion of myosin function by E.coli

Enteropathogenic E. coli establish close contact with host cells by nucleating localized actin rearrangements and directly evading phagocytosis. lizumi et al. now show in a recent issue of Cell Host and Microbe that the type III secretion effector EspB, initially thought to be involved in the translocation of other bacterial effectors, mediates antiphagocytosis and microvilli lesions by inhibiting myosin function.