期刊
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
卷 42, 期 2, 页码 240-243出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.dci.2013.09.004
关键词
Crithidia bombi; Antimicrobial peptides; RNAi; Gut microbiota
Bumblebees, amongst the most important of pollinators, are under enormous population pressures. One of these is disease. The bumblebee and its gut trypanosome Crithidia bombi are one of the fundamental models of ecological immunology. Although there is previous evidence of increased immune gene expression upon Crithidia infection, recent work has focussed on the bumblebee's gut microbiota. Here, by knocking down gene expression using RNAi, we show for the first time that antimicrobial peptides (AMPs) have a functional role in anti-Crithidia defense. (C) 2013 Elsevier Ltd. All rights reserved.
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