4.7 Article

Rh(III)-Catalyzed C-H Amidation of Indoles with Isocyanates

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JOURNAL OF ORGANIC CHEMISTRY
卷 80, 期 14, 页码 7243-7250

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AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b00763

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资金

  1. National Research Foundation of Korea (NRF) - Korea Government (MSIP) [2013R1A2A2A01005249, 2013R1A1A2058800]
  2. National Research Foundation of Korea [2013R1A2A2A01005249, 2013R1A1A2058800] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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The rhodium(III)-catalyzed direct amidation of indoles and pyrroles with aryl and alkyl isocyanates is described. These transformations provide a facile and efficient construction of C-2-amidated N-heterocyclic scaffolds.

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