期刊
DEVELOPMENT GROWTH & DIFFERENTIATION
卷 55, 期 1, 页码 149-163出版社
WILEY
DOI: 10.1111/dgd.12017
关键词
evolution; limb field specification; limb initiation
资金
- Ministry of Education, Science and Culture of Japan [24113508]
- Nakajima Foundation
- Torey Science and Technology Grant
- Naito Foundation
- Inamori Foundation
- Grants-in-Aid for Scientific Research [24113508] Funding Source: KAKEN
Specification of limb field and initiation of limb development involve multiple steps, each of which is tightly regulated both spatially and temporally. Recent developmental analyses on various vertebrates have provided insights into the molecular mechanisms that specify limb field and have revealed several genetic interactions of signals involved in limb initiation processes. Furthermore, new approaches to the study of the developmental mechanisms of the lateral plate mesoderm of amphioxus and lamprey embryos have given us clues to understand the evolutionary scenarios that led to the acquisition of paired appendages during evolution. This review highlights such recent findings and discusses the mechanisms of limb field specification and limb bud initiation during development and evolution.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据