4.7 Article

Metal-Free Oxidative Spirocyclization of Alkynes with Sulfonylhydrazides Leading to 3-Sulfonated Azaspiro[4,5]trienones

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 80, 期 10, 页码 4966-4972

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b00361

关键词

-

资金

  1. National Natural Science Foundation of China [21302109, 21302110, 21375075]
  2. Taishan Scholar Foundation of Shangdong Province
  3. Excellent Middle-Aged and Young Scientist Award Foundation of Shangdong Province [BS2013YY019]
  4. Scientific Research Foundation of Qufu Normal University [BSQD 2012020]

向作者/读者索取更多资源

A novel and direct oxidative spirocyclization of arylpropiolamides with sulfonylhydrazides leading to 3-sulfonated azaspiro[4,5]trienones has been developed under metal-free conditions. The reaction is performed in a tandem: manner constituted by the sequential sulfonylation of alkynes, ipso-carbocyclization, dearomatization, hydration, and oxidation processes, providing a convenient and efficient approach to Various sulfonated,azaspiro[4,5] trienones of biological importance.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据