期刊
DEVELOPMENT
卷 137, 期 12, 页码 1939-1952出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/dev.044511
关键词
Axon guidance; Cell migration; Cell-cell interaction
资金
- Agence nationale de la recherche (ANR)
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Ecole des neurosciences de Paris (ENP)
- Fondation pour la Recherche medicale (Programme equipe FRM)
In most tissues, the precise control of cell migration and cell-cell interaction is of paramount importance to the development of a functional structure. Several families of secreted molecules have been implicated in regulating these aspects of development, including the Slits and their Robo receptors. These proteins have well described roles in axon guidance but by influencing cell polarity and adhesion, they participate in many developmental processes in diverse cell types. We review recent progress in understanding both the molecular mechanisms that modulate Slit/Robo expression and their functions in neural and non-neural tissue.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据