相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Systems biology of human epilepsy applied to patients with brain tumors
Sandeep Mittal et al.
EPILEPSIA (2013)
DNA Methylation in Cancer: A Gene Silencing Mechanism and the Clinical Potential of Its Biomarkers
Shinichi Fukushige et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2013)
Nanotoxicology: in Vitro-in Vivo Dosimetry
Guenter Oberdoerster
ENVIRONMENTAL HEALTH PERSPECTIVES (2012)
Advancing the Next Generation of Health Risk Assessment
Ila Cote et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2012)
Cross-species Comparisons of Transcriptomic Alterations in Human and Rat Primary Hepatocytes Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin
Michael B. Black et al.
TOXICOLOGICAL SCIENCES (2012)
A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2012)
New Directions in Toxicity Testing
Daniel Krewski et al.
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 32 (2011)
Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment
Richard S. Judson et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2011)
Linear low-dose extrapolation for noncancer health effects is the exception, not the rule
Lorenz R. Rhomberg et al.
CRITICAL REVIEWS IN TOXICOLOGY (2011)
Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential
Sumit Gangwal et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2011)
Quantitative knowledge-based analysis in compound safety assessment
Svetlana Bureeva et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2011)
Biomonitoring-based risk assessment for hexabromocyclododecane (HBCD)
Lesa L. Aylward et al.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2011)
Human biomonitoring as a pragmatic tool to support health risk management of chemicals - Examples under the EU REACH programme
Peter J. Boogaard et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2011)
Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2011)
SAR/QSAR methods in public health practice
Eugene Demchuk et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Systems Biology: An Approach
P. Kohl et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Modification by ALAD of the Association between Blood Lead and Blood Pressure in the US Population: Results from the Third National Health and Nutrition Examination Survey
Franco Scinicariello et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
What Role for Biologically Based Dose-Response Models in Estimating Low-Dose Risk?
Kenny S. Crump et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
Computational Toxicology: Realizing the Promise of the Toxicity Testing in the 21st Century
Ivan Rusyn et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data
David M. Reif et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
CONCEPT OF ASSESSING NANOPARTICLE HAZARDS CONSIDERING NANOPARTICLE DOSEMETRIC AND CHEMICAL/BIOLOGICAL RESPONSE METRICS
Erik K. Rushton et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2010)
AN ANIMAL PROTECTION PERSPECTIVE ON 21ST CENTURY TOXICOLOGY
Martin L. Stephens
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)
COMPUTATIONAL SYSTEMS BIOLOGY AND DOSE-RESPONSE MODELING IN RELATION TO NEW DIRECTIONS IN TOXICITY TESTING
Qiang Zhang et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)
VIRTUAL TISSUES IN TOXICOLOGY
Imran Shah et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)
Toxicogenomic profiling of chemically exposed humans in risk assessment
Cliona M. McHale et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2010)
KEGG for representation and analysis of molecular networks involving diseases and drugs
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2010)
A Bayesian Network Model for Biomarker-Based Dose Response
C. Eric Hack et al.
RISK ANALYSIS (2010)
Human and Rat Primary Hepatocyte CYP1A1 and 1A2 Induction with 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 2,3,4,7,8-Pentachlorodibenzofuran
Robert A. Budinsky et al.
TOXICOLOGICAL SCIENCES (2010)
Interpreting NHANES biomonitoring data, cadmium
Patricia Ruiz et al.
TOXICOLOGY LETTERS (2010)
State-of-the-Science Workshop Report: Issues and Approaches in Low-Dose-Response Extrapolation for Environmental Health Risk Assessment
Ronald H. White et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2009)
Molecular networks as sensors and drivers of common human diseases
Eric E. Schadt
NATURE (2009)
Toxicity Testing in the 21st Century: Bringing the Vision to Life
Melvin E. Andersen et al.
TOXICOLOGICAL SCIENCES (2009)
Metabolomics: A global biochemical approach to drug response and disease
Rima Kaddurah-Daouk et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
IPCS framework for analyzing the relevance of a noncancer mode of action for humans
Alan R. Boobis et al.
CRITICAL REVIEWS IN TOXICOLOGY (2008)
Concordance between in vitro and in vivo dosimetry in the proinflammatory effects of low-toxicity, low-solubility particles: The key role of the proximal alveolar region
K. Donaldson et al.
INHALATION TOXICOLOGY (2008)
Metabolic syndrome: from epidemiology to systems biology
Aldons J. Lusis et al.
NATURE REVIEWS GENETICS (2008)
Evidence-based dose-response assessment for thyroid tumorigenesis from acrylamide
Michael Dourson et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2008)
Guidelines for the derivation of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop
Sean M. Hays et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2008)
Systems Biology and Mode of Action Based Risk Assessment
Stephen W. Edwards et al.
TOXICOLOGICAL SCIENCES (2008)
Novel technologies for the discovery and quantitation of biomarkers of toxicity
Fitz B. Collings et al.
TOXICOLOGY (2008)
Dose response considerations in risk assessment - An overview of recent ILSI activities
Michael R. Holsapple et al.
TOXICOLOGY LETTERS (2008)
Applications of metabolomics in drug discovery and development
David S. Wishart
DRUGS IN R&D (2008)
Computational toxicology - A state of the science mini review
Robert J. Kavlock et al.
TOXICOLOGICAL SCIENCES (2008)
BMDExpress: a software tool for the benchmark dose analyses of genomic data
Longlong Yang et al.
BMC GENOMICS (2007)
A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2007)
Estimating risk from ambient concentrations of acrolein across the United States
Tracey J. Woodruff et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2007)
A statistical model for assessing genetic susceptibility as a risk factor in multifactorial diseases: Lessons from occupational asthma
Eugene Demchuk et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2007)
Genotoxicity of poorly soluble particles
Roel P. F. Schins et al.
INHALATION TOXICOLOGY (2007)
Assessing biomarker use in risk assessment - A survey of practitioners
A Maier et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2004)
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
KE Lohmueller et al.
NATURE GENETICS (2003)
The use of biologically based modeling in risk assessment
RB Conolly
TOXICOLOGY (2002)
Differential sensitivity of children and adults to chemical toxicity - II. Risk and regulation
M Dourson et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2002)
Toxicology and genetic toxicology in the new era of toxicogenomics: impact of -omics technologies
MJ Aardema et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2002)
Time extrapolation and interspecies extrapolation for locally acting substances in case of limited toxicological data
R Kalberlah et al.
ANNALS OF OCCUPATIONAL HYGIENE (2002)
Susceptibility differences in chemical carcinogenesis linearize the dose-response relationship: threshold doses can be defined only for individuals
WK Lutz
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2001)
Harmonization of cancer and noncancer risk assessment: Proceedings of a consensus-building workshop
MS Bogdanffy et al.
TOXICOLOGICAL SCIENCES (2001)
Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies
LJ Lesko et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)
Pneumoconiosis-related lung cancers - Preferential occurrence from diffuse interstitial fibrosis-type pneumoconiosis
M Katabami et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)