期刊
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
卷 42, 期 1, 页码 87-94出版社
WILEY
DOI: 10.1111/jog.12834
关键词
dietary exposure; epidemiology; risk factors; uterine fibroids
资金
- Maternal and Child Healthcare Project of Jiangsu Province Health Department [F201407]
- Youth Fund Project of Jiangsu Province Health Department [Q201305]
- Science and Technology Project of Nanjing City [201201054]
- National Natural Science Pre-research Project Funds of Southeast University [3290001102]
- SRTP Project of Southeast University [T11431001]
AimThe aim of this study was to investigate whether a vegetarian diet correlates with a potential reduced risk of uterine fibroids. Material and MethodsWe used data from a case-control study conducted in Southeast University Zhongda Hospital between February 2010 and December 2014. Cases included 600 Chinese Han women with uterine fibroids (case group) whose clinical diagnosis dated back no more than 1 year. Controls were 600 patients without uterine fibroids as well as healthy volunteers (control group). All of the information gathered through the questionnaire survey was analyzed for the risk factors of the uterine fibroids pathogenesis. ResultsThe multifactor analysis showed that women with uterine fibroids reported a less frequent consumption of broccoli (odds ratio [OR]: 0.552; 95% confidence interval [CI]: 0.316-0.964), cabbage (OR: 0.446; 95%CI: 0.211-0.943), Chinese cabbage (OR: 0.311; 95%CI: 0.102-0.946), tomato (OR: 0.453; 95%CI: 0.241-0.853), and apple (OR: 0.416; 95%CI: 0.213-0.814) (P < 0.05). ConclusionThe original evidence from this epidemiological investigation shows that a high consumption of broccoli, cabbage, Chinese cabbage, tomato and apple seems to be a protective factor for uterine fibroids. We suggest that greater intake of fresh fruits and cruciferous vegetables may be able to reduce the incidence of uterine fibroids.
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