4.4 Article

Hidradenitis Suppurativa Complicating Naevus Comedonicus: The Possible Influence of Mechanical Stress on the Development of Hidradenitis Suppurativa

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DERMATOLOGY
卷 220, 期 4, 页码 323-325

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KARGER
DOI: 10.1159/000287261

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Hidradenitis suppurativa, pathogenesis; Naevus comedonicus; Hair follicle strain, mechanical stress

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Naevus comedonicus is a rare, benign hamartoma consisting of grouped abnormal hair follicles and, occasionally, associated with other diseases. We describe an infant who developed hidradenitis-like lesions in an inguinal naevus comedonicus following increased mechanical stress on the region. It is speculated that the degree of strain on a hair follicle is increased when its diameter is increased, leading to wall ruptures. We hypothesise that this serendipitous observation provides a model for the way mechanical stress can account for the development of hidradenitis suppurativa in some patients. Copyright (C) 2010 S. Karger AG, Basel

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