期刊
DERMATOLOGIC THERAPY
卷 23, 期 5, 页码 514-522出版社
WILEY
DOI: 10.1111/j.1529-8019.2010.01354.x
关键词
aging; atrophic vagina; atrophic vaginitis; estrogen deficiency; estrogen replacement therapy; menopause; perimenopause; vaginitis; vulvar diseases
类别
With the loss of estrogen that occurs with menopause, physiologic and structural changes occur within the vulvovaginal mucosa that lead to a condition commonly called atrophic vaginitis. Although mild genital changes occur in most women, 10-47% of postmenopausal women will develop one or more debilitating symptoms that include vulvovaginal dryness, dyspareunia, vulvar itching or pain, recurrent urinary tract infections, as well as abnormal vaginal discharge. Topical estrogen replacement therapies reverse these mucosal changes and are effective treatments for the symptoms of atrophic vaginitis. Vaginal moisturizers and lubricants also provide symptomatic relief for vaginal dryness and dyspareunia, respectively.
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