Nonablative Fractional Laser Resurfacing

Nonablative fractional resurfacing (NFR) uses a mode of delivery with preservation of the stratum corneum, a true resurfacing with epidermal extrusion, and creation of microscopic thermal zones of injury that ultimately lead to neocollagenesis. This article discussed the science, clinical indications, patient selection and preparation, post-treatment care, and complications of NFR. It concludes that the most impressive clinical results are seen with acne scars, surgical and traumatic scars, and mild to moderate facial and nonfacial clyschromia or photoaging. Modest results can be seen with therapy-resistant melasma and certain types of rhytides. Future approaches include synergistic treatments with radiofrequency devices and the development of novel wavelengths to enhance the efficacy of NFR while preserving safety.