期刊
DERMATOLOGIC CLINICS
卷 26, 期 4, 页码 569-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2008.05.004
关键词
Lipoatrophy; Lipodystrophy; HIV infection; AIDS
类别
资金
- NCATS NIH HHS [UL1 TR001105] Funding Source: Medline
- NCRR NIH HHS [UL1 RR024982, KL2 RR024983] Funding Source: Medline
- NIDDK NIH HHS [R01 DK105448] Funding Source: Medline
Lipodystrophy Syndromes comprise a group of rare, heterogeneous disorders characterized by progressive loss of fat tissue, mainly from subcutaneous compartment and occasionally affecting visceral fat. Lipoatrophy may be partial, localized, or generalized. The latter cases are usually accompanied by metabolic-related disorders, including insulin resistance, diabetes mellitus, hyperlipemia, progressive hepatic disease and anabolic state. Treatment for lipodystrophy has increased interest in recent years because a new lipoatrophic population-patients who have HIV-associated lipodystrophy-is much more numerous than the whole number of patients affected by classic lipodystrophy entities.
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