Resin-based composite performance: Are there some things we can't predict?

Objective. The objective of this manuscript is to address the following questions: Why do direct dental composite restorative materials fail clinically? What tests may be appropriate for predicting clinical performance? Does in vitro testing correlate with clinical performance? Methods. The literature relating to the clinical and laboratory performance of dental composite restorative materials was reviewed. The main reasons for failure and replacement of dental composite restorations provided the guidance for identifying specific material's properties that were likely to have the greatest impact on clinical outcomes. Results. There are few examples of studies showing correlation between laboratory tests of physical or mechanical properties and clinical performance of dental composites. Evidence does exist to relate clinical wear to flexure strength, fracture toughness and degree of conversion of the polymer matrix. There is evidence relating marginal breakdown to fracture toughness. Despite the fact that little confirmatory evidence exists, there is the expectation that clinical fracture and wear relates to resistance to fatigue. Only minimal evidence exists to correlate marginal quality and bond strength in the laboratory with clinical performance of bonded dental composites. Significance. The use of clinical trials to evaluate new dental composite formulations for their performance is expensive and time consuming, and it would be ideal to be able to predict clinical outcomes based on a single or multiple laboratory tests. However, though certain correlations exist, the overall clinical success of dental composites is multi-factorial and therefore is unlikely to be predicted accurately by even a battery of in vitro test methods. (c) 2012 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.