期刊
DENTAL MATERIALS
卷 28, 期 3, 页码 298-303出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.dental.2011.11.002
关键词
Meta-analysis; Systematic review; Pit and fissure sealants; Clinical studies; Caries prevention
Objective. This meta-analysis investigates the clinical retention of pit and fissure sealants in relation to observation time and material type. Data, sources and study selection. A search in the MEDLINE, EMBASE and CENTRAL databases identified 2944 abstracts (published prior to 9/30/2011), of which 485 clinical publications were analyzed in detail. A total of 146 articles included information about sealant retention, with a minimum observation time of 2 years. These publications were analyzed to determine the retention rates of the various materials studied (UV-light-, light-and auto-polymerizing resin-based sealants, fluoride-releasing materials, compomers, flowable composites and glass-ionomer-cement-based sealants). The meta-analysis used random effects models for longitudinal logistic regression and Bayesian statistics. Results. As part of the systematic review, 98 clinical reports and 12 field trial reports were identified. Auto-polymerizing sealants had the longest observation time (up to 20 years) and were found to have a 5-year retention rate of 64.7% (95% CI=57.1-73.1%), which was estimated from the meta-analysis model. Resin-based light-polymerizing sealants and fluoride-releasing products showed similar 5-year retention rates (83.8%, 95% CI=54.9-94.7% and 69.9%, 95% CI=51.5-86.5%, respectively) for completely retained sealants. In contrast to these high retention rates, poor retention rates were documented for UV-light-polymerizing materials, compomers and glass-ionomer-cement-based sealants (5-year retention rates were <19.3%). Retention rates for UV-light-polymerizing materials, compomers and glass-ionomer-cement-based sealants were classified as inferior. Conclusions versus Significance. The results of this meta-analysis suggested that resin-based sealants can be recommended for clinical use. The faster and less error-prone clinical application of light-polymerizing materials, however, makes them the preferred choice for daily dental practice. (C) 2011 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据