4.2 Article

Quality of Life among Elderly Patients with Dementia in Institutions

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DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
卷 31, 期 6, 页码 435-442

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KARGER
DOI: 10.1159/000328969

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Depression; Dementia; Quality of life; Factor analysis; Correlates

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Aim: To study quality of life among the elderly with dementia in institutions. Methods: Patients above 60 years with dementia, 82 in nursing home and 74 in departments of geriatric psychiatry, were included. They were assessed with the Quality of Life in Late-Stage Dementia (QUALID); the Self-Maintenance scale, Mini Mental State Examination (MMSE) and Clinical Dementia Rating scale. Patient's age, gender, previous medical and psychiatric history were recorded. Dementia was diagnosed according to ICD-10 criteria for research. Based on information in an interview with the patient and a carer and information in the patient's record, a geriatric psychiatrist made a diagnosis of major depression according to DSM-IV, if present. Results: The patients' mean (+/- SD) age was 82.9 +/- 7.7 years, 103 (66%) were women. A factor analysis of the QUALID scale resulted in two factors: 'discomfort' and 'comfort'. Three linear regression analyses were performed. Variables associated with lower quality of life (total QUALID score) were: a diagnosis of major depression (p < 0.001), lower score on MMSE (p = 0.032), impaired function in activities of daily living (p = 0.007) and female gender (p = 0.046). Variables associated with the 'discomfort' subscale score were: major depression (p < 0.001), lower score on MMSE (p = 0.006) and living in a department of geriatric psychiatry (p = 0.041). The 'comfort' subscale score was associated with impaired function in activities of daily living (p < 0.001). Explained variance for the three models was 34, 33 and 23%, respectively. Conclusion: Quality of life is diminished among elderly patients in institutions and the most marked correlates were a diagnosis of major depression, worse performance in activities of daily living and worse cognitive function. Copyright (C) 2011 S. Karger AG, Basel

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