期刊
DALTON TRANSACTIONS
卷 43, 期 16, 页码 6244-6250出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3dt53396d
关键词
-
资金
- National Natural Science Foundation of China [21171035, 51302035]
- Chinese Ministry of Education [313015]
- PhD Programs Foundation of the Ministry of Education of China [20110075110008, 20130075120001]
- National 863 Program of China [2013AA031903]
- Science and Technology Commission of Shanghai Municipality [13ZR1451200]
- Fundamental Research Funds for the Central Universities
- Hong Kong Scholars Program
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1221]
- Shanghai Leading Academic Discipline Project [B603]
- Program of Introducing Talents of Discipline to Universities [111-2-04]
Photothermal therapy (PTT) is limited by unsuitable photothermal agents and near-infrared (NIR) light. Herein, self-assembled PEGylated WO3-x hierarchical nanostructures, which could serve as excellent laser-cavity mirrors, were successfully prepared via a simple one-pot solvothermal route. The as-prepared WO3-x hierarchical nanostructures displayed strong near-infrared absorption. The absorption of pure water at 980 nm is 30 times higher than that at 915 nm, and the temperature of water only increased by 3.4 degrees C under the irradiation of a 915 nm laser with a power density of 1.0 W cm(-2) for 10 min, while the temperature of water increased as much as 15.1 degrees C for the 980 nm laser. With continuous excitation by 915 nm light, the photothermal conversion efficiency of these WO3-x hierarchical nanostructures was evaluated to be 28.1%. Thus, the WO3-x hierarchical nanostructures could serve as excellent laser-cavity mirrors of a 915 nm laser. The PTT study on cancer cells in vivo demonstrated that the WO3-x hierarchical nanostructures can generate enough heat for efficient photothermal therapy of cancer cells under the irradiation of a 915 nm laser with a power density of 1.2 W cm(-2) over a short period (5-10 min).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据