期刊
DALTON TRANSACTIONS
卷 41, 期 45, 页码 13803-13806出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2dt31880f
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资金
- Deutsche Forschungsgemeinschaft [SFB 824, B5, Z1]
The 1,4,7-triazacyclononane-1,4,7-tris(methylenephosphinic acid) chelators TRAP and NOPO are complexing copper-64 with similar efficiency as 1,4,7-triazacyclononane- triacetic acid (NOTA). The kinetic stability of Cu-64-labelled TRAP-peptides is sufficient for PET imaging at early time points (1-2 h post injection). For labelling of TRAP conjugates, Cu-64 can be recommended as an alternative to Ga-68 to achieve higher resolution of PET images.
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