期刊
CYTOTHERAPY
卷 12, 期 3, 页码 429-431出版社
INFORMA HEALTHCARE
DOI: 10.3109/14653241003587637
关键词
chronic wound healing; dystrophic epidermolysis bullosa; mesenchymal stromal cell
In animal models it has been shown that mesenchymal stromal cells (MSC) contribute to skin regeneration and accelerate wound healing. We evaluated whether allogeneic MSC administration resulted in an improvement in the skin of two patients with recessive dystrophic epidermolysis bullosa (RDEB; OMIM 226600). Patients had absent type VII collagen immunohistofluorescence and since birth had suffered severe blistering and wounds that heal with scarring. Vehicle or 0.5x10
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