期刊
CYTOTHERAPY
卷 11, 期 6, 页码 676-687出版社
ELSEVIER SCI LTD
DOI: 10.3109/14653240903313974
关键词
biomarker; Clara cell secretory protein; lung; regeneration; stem cells
Clara cell secretory protein ( CCSP) is one of the most abundant proteins in the airway surface fluid, and has many putative functions. Recent advances in the field of stem cells and lung regeneration have identified potentially new roles of CCSP and CCSP-expressing cell populations in airway maintenance, repair and regeneration. This review focuses on the airway regenerative potential of CCSP and the cells that express this protein. The use of this protein or CCSP-expressing cells as an indication of biologic processes that contribute to lung injury or repair is highlighted.
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