期刊
CYTOMETRY PART A
卷 77A, 期 3, 页码 220-230出版社
WILEY
DOI: 10.1002/cyto.a.20860
关键词
pyroglutamyl proline-rich oligopeptides; calcium signaling; G-protein coupled receptor; neurotransmitter release; cardiovascular homeostasis; neuronal cells; snake peptide; calcium imaging by confocal microscopy; fluorescence imaging plate reader analysis
资金
- FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Brazil
Pyroglutamyl proline-rich oligopeptides, present in the venom of the pit viper Bothrops jararaca (Bj-PROs), are the first described naturally occurring inhibitors of the angiotensin I-converting enzyme (ACE). The inhibition of ACE by the decapeptide Bj-PRO-10c (
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