期刊
CYTOGENETIC AND GENOME RESEARCH
卷 126, 期 1-2, 页码 77-85出版社
KARGER
DOI: 10.1159/000245908
关键词
Evolution; FISH; Gene mapping; Goat; Human
资金
- National Research Council of Rome, Italy [DG.RSTL.083.001, DG.RSTL.083.002]
- LR5 of Campania Region, Italy
Few goat genome analysis projects have been developed in the last 10 years. The aim of this review was to compile and update all available cytogenetic mapping data, according to the last goat chromosome nomenclature, as well as human and cattle whole genome sequences. In particular, human regions homologous to most of the FISH-mapped microsatellites were identified in silico. This new goat cytogenetic map made it possible to refine delineation of conserved segments relative to the human and cattle genomic sequence. These improvements did not lead to detection of major new rearrangements within ruminants but confirmed the good conservation of synteny and the numerous intrachromosomal rearrangements observed between goats and humans. Copyright (C) 2009 S. Karger AG, Basel
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