期刊
CURRENT TOPICS IN MEDICINAL CHEMISTRY
卷 14, 期 7, 页码 952-965出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1568026614666140202210424
关键词
Trifluoromethyl group; heterocycles
资金
- U.S. Department of Energy
- National Institutes of Health
- U.S. Department of Energy [DE-AC05-00OR22725]
This review is a follow-up to the previous chapter, Monofluorinated Heterocycles (Topics in Heterocyclic Chemistry, 2012, 33-63), and presents an overview of synthetic chemistry of heterocycles with only one trifluoromethyl group directly attached to the ring (trifluoromethylated heterocycles). Particular attention is given to the modern direct trifluoromethylation methods, including catalytic reactions, organometallic reagents, carbene and hypervalent chemistry, utilization of ionic nucleophilic and electrophilic trifluoromethylating agents, and to other pertinent trends. One of the emphases of the review is compounds with biomedical potential.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据