Conformational Preferences of Chiral Acyclic Homooligomeric beta(2,2)-Peptides

alpha-Methylisoserine, a chiral acyclic quaternary beta-amino acid, has been used to mimic secondary structures, when it is incorporated in a homogeneous beta(2,2)-dipeptide. In particular, the observed folded conformations in aqueous solution can be regarded as mimics of beta-turn.