期刊
CURRENT TOPICS IN MEDICINAL CHEMISTRY
卷 11, 期 19, 页码 2457-2471出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/156802611797470376
关键词
Slow-wave sleep; Slow oscillation; sleep; thalamocortical; states of vigilance
资金
- CIHR Funding Source: Medline
- NINDS NIH HHS [R01 NS060870] Funding Source: Medline
This article starts with a brief review of the thalamocortical system architecture, which is composed of the projecting thalamic nuclei, the thalamic reticular nucleus, and the neocortex. Then we provide a description of the three states of vigilances followed by a detailed review of major brain rhythms present in the thalamocortical system, ranging from very slow to very fast oscillations. We provide descriptions of known mechanisms and hypotheses for unknown mechanisms for the generation of the different rhythms. The last part offers a detailed review on sleep slow oscillation describing its properties in the thalamocortical system, proposing a mechanism of generation of active states and a description of their propagation.
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