期刊
CURRENT TOPICS IN MEDICINAL CHEMISTRY
卷 9, 期 16, 页码 1546-1559出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/156802609789909795
关键词
Low molecular weight chitosan (LMWC); chitosan oligosaccharide (COS); preparation; analytical method; bioactivity
资金
- Hi-Tech Research and Development Program of China (863 Programs) [2006AA100313, 2007AA10Z343]
- Chinese Academy of Sciences [KSCX 2-3-02-04]
Chitosan is one of the most abundant marine-based biopolymers. Low molecular weight and oligomeric chitosans are water-soluble hydrolysates of chitosan. They have been shown to have a wide range of biological activities and industrial applications. In particular, low molecular weight and oligomeric chitosans have been reported to have the health benefits such as immunity regulation, anti-tumor, liver protection, blood lipids lowering, anti-diabetic, antioxidant and anti-obesity. In this paper, the preparation and analytical methods, and bioactivities of these low molecular weight and oligomeric chitosans were reviewed, with the latest progresses introduced and discussed.
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