期刊
CURRENT PHARMACEUTICAL DESIGN
卷 15, 期 22, 页码 2632-2636出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138161209788957519
关键词
Diffusion imaging; white matter; prefrontal cortex; hippocampus; amygdala; corpus callosum; lithium; valproate
资金
- American Psychiatric Institute for Research and Education (APIRE Young Minds in Psychiatry Award)
- Italian Ministry for University and Research and the Italian Ministry of Health
- [MH 69774]
- [MH 68766]
- [RR 20571]
In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.
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