4.3 Review

Asymmetric epoxidation of electron-deficient olefins

期刊

CURRENT ORGANIC SYNTHESIS
卷 5, 期 3, 页码 186-216

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017908785133429

关键词

asymmetric epoxidation; electron deficient olefins; organocatalysis; dioxiranes; chiral ligand-metal peroxide systems; Julia-Colonna epoxidation

资金

  1. Spanish MEC
  2. CICYT [CTQ2006-08296]
  3. FSE
  4. Junta de Castilla y Leon [SA007A06]
  5. Universidad de Salamanca

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This paper focuses on the latest developments in asymmetric epoxidation of electron-deficient olefins since the review by Porter and Skidmore on chiral ligand-metal peroxide systems, polyamino acid catalysed and organocatalysed epoxidations. Particular attention has been paid to the most recent advances using chiral pyrrolidines as organocatalysts.

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