4.5 Article

Microwave-Assisted Multicomponent Synthesis of Heterocycles

期刊

CURRENT ORGANIC CHEMISTRY
卷 15, 期 2, 页码 204-236

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BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527211793979817

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Combinatorial Chemistry; Heterocycles; Microwaves; Multicomponent reactions; One-Pot Reactions; Organic Synthesis; Reaction Efficiency

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Multicomponent reactions are valuable tools for the generation of diverse heterocycles. As in many fields or organic chemistry, microwave irradiation is rapidly replacing conventional heating methods in multicomponent chemistry. In this review, we present an overview of recent applications of the use of microwaves in multicomponent heterocycle synthesis. Where possible, the yield and chemo-, regio- and stereoselectivity of microwave-assisted reactions are compared with those using conventional heating.

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